best treatment for damaged hair Alzheimer’s disease and prion diseases: What they may have in common? (13)

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Exclusive interview / Dr. Anton Titov MD and Professor Dr. Sebastian Brandner, expert in molecular and genetic brain tumor diagnosis and neurodegeneration.

Just to circle back to the concept of CJD, and also Alzheimer's disease, there is a genetic influence, but it can also arise spontaneously. The vast majority, 95% of cases are spontaneous.

- 95% [of Alzheimer's or CJD] cases are spontaneous, but once disease happens, it can be transmitted via the biological material... - Yes, that's right! I would say very clearly, via medical procedures where brain tissue is transmitted in some way. We don't yet know how risky that is, how common that is, whether it's easy or difficult. And we should also say, it's not that we can transmit Alzheimer's disease, we can transmit the protein that then deposits and amplifies in the recipient brain, and, it was established, this protein can cause some problems in the blood vessels, they then become more brittle and they start bleeding. We have seen a few examples, where the transmission without prion disease was also possible, and that leads young people to the potential development of these vascular problems, which we call cerebral amyloid angiopathy. This is a whole different concept of disease!

- Yes, that's right! - It's amazing, these diseases are not bacterial and not viral, but are caused by a protein that can precipitate intrinsic changes.
- Yes...
- Huge implications!

best treatment for damaged hair Alzheimer’s disease and prion diseases: What they may have in common? (13)
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